Publications

For the most recent listing of MEDLINE-indexed articles, see PubMed.

MacLea, K.S., Paul, K.R., Ben-Musa, Z.**, Waechter, A.*, Shattuck, J.E.**, Gruca, M.*, and Ross, E.D.  Distinct amino acid compositional requirements for formation and maintenance of the [PSI+] prion in yeast.  Mol Cell Biol, 35(5):899-911. doi: 10.1128/MCB.01020-14, 2015.

Abuhagr, A.M.**, MacLea, K.S., Chang, E.S., and Mykles, D.L.  Mechanistic target of rapamycin (mTOR) signaling genes in decapod crustaceans: cloning and tissue expression of mTOR, Akt, Rheb, and S6 kinase in the green crab, Carcinus maenas, and blackback land crab, Gecarcinus lateralis. Comp Biochem Physiol A, 168:25-39. doi: 10.1016/j.cbpa.2013.11.008, 2014.

Abuhagr, A.M.**, Blindert, J.L.**, Nimitkul, S.**, Zander, I.A.*, LaBere, S.M.*, Chang, S.A., MacLea, K.S., Chang, E.S., and Mykles, D.L.  Molt regulation in green and red color morphs of the crab, Carcinus maenas: gene expression of molt-inhibiting hormone signaling components.  J Exp Biol, 217:796-808. doi: 10.1242/jeb.093385, 2014.

Kim, H.J., Kim, N., Wang, Y., Moore, J., Diaz, Z., Scarborough, E, Ugras, S., MacLea, K.S., Freibaum, B., Molliex, A., Kanagaraj, A., Songqing, L., Pinkus, J., Greenberg, S., Trojanowski, J., Traynor, B., Smith, B., Topp, S., Gkazi, A.-S., Miller, J., Shaw, C.E., Kottlors, M., Kirschner, J., Pestronk, A., Li, Y., Gitler, A., Benatar, M., King, O., Kimonis, V., Ross, E.D., Weihl, C., Shorter, J., and Taylor, J.P.  Mutations in prion-like domains found in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy.  Naturedoi:10.1038/nature11922, 495(7442):467-73, 2013.

Ross, E.D., MacLea, K.S., Anderson, C., and Ben-Hur, A.  A bioinformatics method for identifying Q/N-rich prion-like domains in proteins.  In Hatters DM and Hannan AJ (eds.), Tandem Repeats in Genes, Proteins, and Disease: Methods and Protocols, Methods Mol Biol, doi:10.1007/978-1-62703-438-8_16, 1017:219-228, 2013.

MacLea, K.S., Abuhagr, A.M.**, Pitts, N.L.**, Covi, J.A., Bader, B.D.*, Chang, E.S., and Mykles, D.L.  Rheb, an activator of the mTOR complex, in the blackback land crab, Gecarcinus lateralis: cloning and effects of molting on expression in skeletal muscle.  J Exp Biol, 215(4):590-604, doi:10.1242/jeb.062869, 2012.

MacLea, K.S.  Book review of Laura L. Mays Hoopes, Breaking Through the Spiral Ceiling: An American Woman Becomes a DNA Scientist. J Hist Biol, doi:10.1007/s10739-012-9320-1, 45(2), 357-360, 2012.

MacLea, K.S. and Ross, E.D.  Strategies for identifying new prions in yeast.  Prion, 5(4):1-6, 2011.

MacLea, K.S., Covi, J.A., Kim, H.-W., Chao, E.**, Medler, S., Chang, E.S., and Mykles, D.L.  Myostatin from the American lobster, Homarus americanus: cloning and effects of molting on expression in skeletal muscles.  Comp Biochem Physiol A, 157:328–337, 2010.

Cheng, H., Niikura, M., Kim, T., Mao, W.**, MacLea, K.S., Hunt, H., Dodgson, J., Burnside, J., Morgan, R., Ouyang, M., Lamont, S., Dekkers, J., Fulton, J., Soller, M., and Muir, W.  Using integrative genomics to elucidate genetic resistance to Marek's disease in chickens, Dev Bio (Basel), 132:365-72, 2008.

MacLea, K.S., and Cheng, H.H. The threat of Marek’s disease virus is expanding. Microbe, 2(5), 238-243, 2007.

MacLea, K.S. and Cheng, H.H.  Cloning and expression of deoxyribonuclease II from chicken, Gene, 373:44-51, doi:10.1016/j.gene.2005.12.019, 2006.

MacLea, K.S., Krieser, R.J., and Eastman, A.  Structural requirements of human deoxyribonuclease IIa for formation of the active enzyme: the role of the signal peptide, N-glycosylation, and disulfide bridging, Biochem J, 371:867-876, 2003. 

MacLea, K.S., Krieser, R.J., and Eastman, A.  A family history of deoxyribonuclease II: Surprises from Trichinella spiralis and Burkholderia pseudomallei.  Gene, 305:1-12, 2003.

Krieser, R.J., MacLea, K.S., Longnecker, D.S., Fields, J.L., Fiering, S., and Eastman, A.  Deoxyribonuclease IIalpha is required for DNA digestion during the phagocytic phase of apoptosis and its loss is perinatal lethal.  Cell Death Differ, 9 (9), 956-962, 2002.

MacLea, K.S., Krieser, R.J., and Eastman, A.  Revised structure of the active form of human deoxyribonuclease IIalphaBiochem Biophys Res Commun, 292 (2), 415-421, 2002. 

Krieser, R.J., MacLea, K.S., Park, J.P., and Eastman, A.  The cloning, genomic structure, localization, and expression of human deoxyribonuclease IIβ.  Gene, 269 (1-2), 205-216, 2001.

* = undergraduate student co-author      ** = graduate student co-author

© Kyle S. MacLea 2015